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KMID : 0360220080490040677
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Journal of the Korean Ophthalmological Society
2008 Volume.49 No. 4 p.677 ~ p.680
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A Case of Post-traumatic Necrobiotic Xanthogranuloma of the Orbit
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Choi Hyun-Joon
Kwon Hee-Jung
Kim Hye-Young
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Abstract
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Purpose: To investigate the role of nitric oxide (NO) on the migration of cultured human Tenon’s capsule
Purpose: Necrobiotic xanthogranuloma is a very rare disease characterized by the presence of yellow subcutaneous skin lesions and systemic paraproteinemia. We report a case of post?traumatic necrobiotic xanthograuloma that presented with a preseptal mass.
Case summary: A 31-year-old man presented with ptosis and a mass on the left superior orbit that developed after trauma 3 weeks prior to admission. A computed tomography scan showed a contrast-enhancing preseptal mass, and surgical exploration was performed.
Conclusions: Histopathological examination revealed a tumor that had all the major features of necrobiotic xanthogranuloma, including fat necrosis with granulomatous inflammation, giant multinucleated cells, foamy cells, and several lymphoid follicles with germinal centers. Hematologic evaluation revealed polyclonal gammopathy.
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KEYWORD
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Necrobiotic xanthogranuloma, Orbital tumor, Paraproteinemia, Polyclonal gammopathy
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